模拟移动床过程的结构优化策略研究

Structure optimal strategy research of simulated moving bed process

模拟移动床(Simulated Moving Bed,SMB)技术作为主要的吸附分离技术,近年来在石油化工、精细化工、生物医药和食品工业中得到广泛的应用。如何基于模拟移动床的机理数学模型进行优化,以提高模拟移动床分离过程的经济效益,是模拟移动床研究领域的热点问题之一。模拟移动床过程具有复杂的动态特性,例如,由于出入口切换带来的混杂、非线性以及延迟特性。另一方面,由于对过程干扰和系统不确定性的高灵敏性,使得模拟移动床过程在操作点处的鲁棒操作仍然是一个研究的重点。以模拟移动床过程为研究背景,在阐述其工作原理的基础上,通过对模拟移动床过程的不同分区情况以及柱配置情况进行研究,得到了模拟移动床模型的结构优化过程描述,然后通过在不同目标函数情况下进行优化结果:的比较,说明模拟移动床过程结构优化的可行性,对进一步的控制方案设计具有一定的指导意义。以模拟移动床过程为研究背景,在阐述其工作原理的基础上,通过对模拟移动床过程的不同分区情况以及柱配置情况进行研究,得到了模拟移动床模型的结构优化过程描述,然后通过在不同目标函数情况下进行优化结果:的比较,说明模拟移动床过程结构优化的可行性,对进一步的控制方案设计具有一定的指导意义。

Simulated moving bed （SMB） technology has emerged as a powerful technique for continuous countercurrent adsorption separation. In the last decade, the SMB applications have expanded greatly in the area of biotechnology, fine chemistry and pharmaceutical industry. How to improve the separation performance of SMB based on the mathematical model is the major problem in the research field of SMB. SMB processes exhibit complex dynamics, e.g., its hybrid nature due to the inlet/outlet port switches with nonlinearities and delays. On the other hand, robust operation of SMB units at their economic optimum is still an open issue because of the high sensitivity of the process performance to disturbances and uncertainties in the system. Simulated Moving Bed process is made as the research background. On the basis of its working principle and through simulated moving bed process different zones and column configurations, simulated moving bed model description of the structure optimization process is gained. Then through comparing different situations of different objective functions, the optimization result shows the feasibility of simulated moving bed structure optimization process. The results have some guiding significances for further design of the control scheme.