摘要
采用放射免疫法观察测定了1985～1987年5月的34例不同程度烧伤病人T_3、T_4值的变化,同时通过30名健康人的检测,建立了T_3、T_4正常值。观察结果表明:烧伤后血清T_3、T_4测定值低于正常人。但T_3的下降趋势与时间呈对数负相关曲线型,而T_4呈正抛物线型。烧伤面积越大,T_3、T_4下降明显。对合并败血症者,T_3、T_4均有明显降低。T_3、T_4的过度低下则提示预后不佳。
From May 1985 to May 1987.dynamic changes in T3 and T4 in serum of 34 burn patietitswere measured by radio-immuodiffusion method.Among them, 10 patients died. The normal levels of T3 and T4 in serum of 30 healthy person are presented. The levelsof T3 and T4 in every burn groups were lower significantly than in normal healthy persongroup (P<0.01). After 3 days of burn injury. the levels of T3 and T4 in serum were lowon 3 days postburn and were lowest on 30 days postburn. T3 in serum was markedly higher before sepsis than after sepsis (P<0.01) and T4 inserum was lower before sepsis than after sepsis. But no significant difference was found(P>0.05). It also showed that the levels of T3. T4 were higher in groups of non-sepsis andsurvival than in those of sepsis and death. The results suggest that determination of T3 and T4 in serum are valuable to diagnose andpredict the prognosis of sepsis in burn injuries.
