低温等离子消融联合利鼻脱敏汤治疗持续性变应性鼻炎疗效观察

Therapeutic effect of low temperature plasma ablation with Libituomin soup on persistent allergic rhinitis

目的探讨低温等离子消融联合利鼻脱敏汤治疗持续性变应性鼻炎(PAR)的疗效。方法 223例PAR患者随机分成2组,治疗组125例给予低温等离子消融术治疗,并联合应用中药利鼻脱敏汤,7 d为1个疗程,服用2个疗程;对照组98例仅给予低温等离子消融治疗。2年后评估临床症状(VAS评分)和生活质量(RQLQ评分)变化。结果 2组治疗后临床症状和生活质量均有明显改善,对照组VAS评分由治疗前的(30.53±2.27)分降至(16.50±5.02)分,治疗组由(31.43±2.42)分降至(13.34±6.17)分,差异有统计学意义(P<0.05);对照组RO、LQ评分由治疗前的(61.00±20.52)分降至(29.05±8.64)分,治疗组由(60.67±22.30)分降至(26.08±9.72)分,差异有统计学意义(P<0.05)。且治疗组均优于对照组(P<0.05)。结论低温等离子消融术联合利鼻脱敏汤治疗PAR疗效明显优于单纯手术治疗。

Objective To evaluate the effect of Libituomin soup （LBTMS） on perennial allergic rhinitis （PAR） as a post-operative combined itherapy during treatment with low temperature plasma ablation （LTPA）. Methods The enrolled pa- tients （ n =223） were divided into two groups, treatment group （ n = 125） received LTPA and intake of LBTMS for 14 days and the control group （ n = 98） of patient received LTPA alone. The clinical symptom （VAS score） and quality of life evalu- ation （ RQLQ score） were carried out after two years. Results Both groups of patients showed clinical relief and improvement of quality of life after these treatments. VAS score from 30.53 ±2.27 to 16.50 ± 5.02 in control group, from 31.43 ± 2.42 to 13,34±6. 17 in treatment group （ P 〈0.05） ; RQLQ score from 61.00 ±20.52 to 29.05 ±8.64 in control group, from 60.67 ± 22 30 tO 26.08± 9.72 in treatment group （ P 〈 0.05）. LTPA and LBTMS group had superior therapeutic effect over LTPA alone group With statistically significant difference （ P 〈 0. 05 ）. Conclusion Combination of LTPA and LBTMS on the treatment of PAR shows better effect over surgical procedure alone.