通窍导浊颗粒治疗慢性细菌性前列腺炎的实验研究

Therapeutic effects of Tongqiao Daozhuo Granules on chronic bacterial prostatitis

目的研究通窍导浊颗粒治疗慢性细菌性前列腺炎的疗效及作用机理.方法通过体外抑菌实验、对大鼠细菌性前列腺炎模型影响的研究,观察通窍导浊颗粒在抑菌、抗炎方面的作用.结果体外研究表明,通窍导浊颗粒对金黄色葡萄球菌、大肠杆菌、表皮葡萄球菌具有显著的抑菌作用.动物试验表明,通窍导浊颗粒对金黄色葡萄球菌和大肠杆菌所致大鼠细菌性前列腺炎有治疗作用.结论通窍导浊颗粒具有抑菌、抗炎的作用,为本品用于慢性细菌性前列腺炎治疗提供了实验依据.

Objective To study the therapeutic effect and mechanism of Tongqiao Daozhuo Granules on chronic bacterial prostatitis.Methods To observe the bacteriostasis and antiinflammatory effects of Tongqiao Daozhuo Granules through bacteriostasis experiment in vitro and studies on bacterial prostatitis model in rats.Results The results in vitro studies indicated that Tongqiao Daozhuo Granules had significant bacteriostatic action on Staphylococcus aureus,Escherichia coli and Staphylococcus epidermidis.Animal experiments indicated that Tongqiao Daozhuo Granules had therapeutic actions on bacterial prostatitis in rats which induced by Staphylococcus aureus and Escherichia coli.Conclusion Tongqiao Daozhuo Granules had bacteriostasis and anti-inflammatory effects.It provided experimental evidences of Tongqiao Daozhuo Granules for the treatment of chronic bacterial prostatitis.