半肝血流阻断在肝癌肝切除术中的临床应用研究

Study on clinical application of hemihepatic vascular control in hepatectomy for hepatoma

目的探讨半肝血流阻断技术在肝癌行肝切除术中的临床意义。方法把76例因肝癌行肝切除术的患者随机分为两组:半肝血流阻断组(HVC组)41例,第一肝门阻断组(Pringle组)35例,对两组患者的术中失血量、手术时间、术后肝功能恢复及并发症发生率等指标进行分析。结果两组手术时间相比,差异无统计学意义,P>0.05。两组患者均顺利完成手术。两组的失血量、肝功能指标、并发症发生率相比,差异有统计学意义,P<0.05。结论半肝血流阻断法比Pringle法在肝癌肝切除术中能更有效地减少术中出血及术后并发症,有利于术后肝功能的恢复。

Objective To discuss the clinical values of hemihepatic vascular control in hepatectomy for hepatoma.Methods 76 patients with hepatoma who underwent hepatectomy were divided into two groups： in group HVC 41 cases and in group Pringle 35 cases.The influence of the two approaches on the parameters including intraoperative blood loss,operative duration,postoperative hepatic function and complications incidence rate were comparatively analyzed.Results Hepatectomy was successfully performed in the two groups.There was no significant difference between the two groups in operative duration（P〈0.05）.Significant difference existed between the two groups in intraoperative blood loss、postoperative hepatic function and in postoperative complications incidence rate（P〈0.05）.Conclusion Compare with Pringle,Hemihepatic vascular control（HVC） would be more effective in reducing operation hemorrhage and complications incidence rate,in favour of the recovery of postoperative hepatic function parameters.