脂肪肝与颈动脉内膜中层厚度的关系

The relationship between fatty liver disease and intimal medial thickness

目的探讨脂肪肝与颈动脉内膜中层厚度(IMT)、颈动脉粥样硬化的关系。方法根据B超检查将研究对象分为脂肪肝组和非脂肪肝组,超声检测两组患者的颈动脉IMT和颈动脉粥样斑块,同时测量身高、体质量,检测血糖、血脂,并对资料进行统计学分析。结果脂肪肝组体质量指数(BMI)、空腹血糖(FPG)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、颈动脉IMT和粥样斑块检出率均明显高于非脂肪肝组(P<0.05)。结论脂肪肝与颈动脉IMT、粥样硬化密切相关,腹部B超检查发现脂肪肝的同时应警惕动脉粥样硬化的可能。

Objective To discuss the relationships among fatty liver disease,intimal medial thickness（IMT） and carotid atherosclerosis. Methods Sixty fatty liver disease patients and sixty control subjects were randomly se- lected in the study. Abdominal ultrasound was taken for fatty liver examination. Ultrasound was taken for intimal medial thickness（IMT） and carotid atherosclerotic plaque examination. Hight, weight, BMI and blood pressure were measured. Biochemical assay was used to determine FPG,TG, TC, HDL-C and LDL-C. The relationships among fatty liver disease,intimal medial thickness（IMT）, carotid atherosclerosis and other ciinical factors above were also ana- lyzed. Results The level of BMI, FPG,TG, LDL-C,IMT and the atheromatous plaque detection rates were signifi- cantly increased in fatty liver disease patients when compared with controls （P〈0.05）. Conclusion Fatty liver dis- ease is closely associated with intimal medial thickness（IMT） and carotid atherosclerosis. The atherosclerosis should be on the alert when abdominal B ultrasonic examination found fatty liver disease.