不同输血对策对早产儿临床预后的影响

The effect of different transfusion measures on the clinical outcome in preterm infants

目的研究不同输血对策对早产儿临床预后的影响。方法接受输血的早产儿共100例，分为限制性输血组与非限制性输血组，观察临床结局情况。结果限制性输血组患儿输血前红细胞比容（Hot）为（27．97±4．86）％，明显低于非限制性输血组患儿输血前的Hot（34．51±6．34）％（t=3．78，P〈0．05）；两组患儿每次输血量、每人输血总量、输血次数，差异无统计学意义（t=0．59、0．37、0．68，均P〉0．05）。非限制性输血组有创呼吸机使用（5．73±4．95）d，明显少于限制性输血组（7．61±5．72）d（t=2．36，P〈0．05）；两组患儿其余临床结局情况，差异均无统计学意义（P〉0．05）。结论非限制性输血可使有创呼吸机使用时间减少，可能更利于早产儿临床恢复，临床上不要一味采取保守的限制性输血对策。

Objective To study the effect of different transfusion measures on the clinical outcome in preterm infants. Methods 100 cases of blood transfusion in preterm infants were chosen. They were divided into restrictive transfusion group and non-restrictive transfusion group. The clinical outcomes of infants were recorded. Results The Hct of children with restrictive transfusion group pre-transfusion was （27.97 ± 4.86） %, which was significantly lower than pre-transfusion Hct of non-restrictive transfusion group（ 34.51 ± 6. 34）%. The difference was statistically significant （ t=3.78, P 〈 0.05 ）. The differences of each transfusion value, each blood transfusion and transfusion times for the two groups of infants were not statistically significant （ t = 0. 59,0. 37,0. 68, all P 〉 0.05 ）. The invasive ventilator of the non-restrictive transfusion group was （5.73 ± 4.95 ）d, significantly less than the restrictive transfusion group（7.61 ± 5.72） d. The difference was statistically significant（ t = 2.36 ,P 〈 0.05 ）. The differences for the rest of the clinical outcomes for the two groups of infants were not statistically significant （ P 〉 0.05 ）. Conclusion The reducing of non-restrictive transfusion invasive ventilator time may be more conducive to clinical recovery in preterm infants. The clinical should not blindly adopt conservative restrictive transfusion countermeasures.