罗哌卡因联合苏芬太尼用于剖宫产术的效果观察

Observation of the effect of ropivacaine combined sufentanil on cesarean section

目的观察罗哌卡因联合苏芬太尼用于剖宫产术的效果。方法140例足月妊娠行剖宫产术的产妇，按随机双盲原则分成两组，治疗组（罗哌卡因10mg＋苏芬太尼5μg）70例，对照组（罗哌卡因10mg）70例。观察比较两组麻醉起效时间、感觉阻滞达最高平面时间、镇痛持续时间、麻醉效果优良率及不良反应发生率。结果治疗组麻醉起效时间、感觉阻滞达最高平面时间较对照组均明显缩短（t=34．512、30．611，均P〈0．01）；镇痛持续时间较对照组明显延长（t=54．732，P〈0．01）；治疗组的麻醉效果优良率为97．14％，明显高于对照组的71．42％（χ2=17．473，P〈0．01）；治疗组不良反应发生率较对照组低（分别为8．57％和57．14％）（χ2=17．473，P〈0．01）。结论罗哌卡因联合苏芬太尼在剖宫产术中能有效延长术后镇痛时间，又能达到满意的麻醉效果，不良反应少，安全有效，值得临床推广。

Objective To approach the effect of ropivacaine combined sufentanil on cesarean section. Methods 140 cases of ASA I - II level full-term pregnancy underwent cesarean section were randomly divided into treatment group（ ropivacaine combined sufentanil, n = 70 ） and control group （ ropivacaine, n = 70 ）. The treatment group was given 10mg ropivacaine and 5 μg sufentanil. The control group was given lOmg ropivacaine. The anesthesia time, analgesic duration and anesthesia effect were compared between two groups. At the same time,intraoperative hypotension,nausea,vomiting,bradycardia,shivering,itching and other adverse reactions were compared. Results The anaesthetic effect（ 97.14% ） of the treatment group （71.42%） was obviously higher than that of the control group （ χ2 = 17. 473, P 〈 0.01 ）. The treatment group work time was significantly shorten, the analgesic duration was also obvious extended （P 〈 0.05 ）. Compared with controls, the nausea, shivers, vomiting and other bad reactions in the treatment group were significantly reduced. The itch incidence between two groups was significantly different between two groups（ t = 54. 732 ,P 〈 0.01 ）. Conclusion The effect of ropivacaine combined sufentanil on cesarean section was confirmed and safe. Combination of these two drugs could prolong the analgesic time and the effect of anesthesia with few adverse effects.