干扰素和易坦静联合治疗婴幼儿毛细支气管炎的疗效观察

Effect of Interferon and Yitanjing on Infants with Bronchiolitis

目的:探讨干扰素和易坦静联合治疗婴幼儿毛细支气管炎的临床疗效。方法:选择笔者所在医院2011年4月-2012年4月收治的婴幼儿毛细支气管炎患者52例,随机分为两组,对照组采用常规综合治疗,包括吸氧、平喘、祛痰等;观察组在常规治疗的基础之上采用干扰素联合易坦静进行治疗,比较两组患儿的临床疗效、症状、体征消失的时间。结果:观察组总治愈率为100%,对照组总有效率65.4%,两组比较,差异有统计学意义(P<0.05)。观察组退热时间、喘憋缓解时间、咳嗽消失时间、肺部哮鸣音消失时间以及住院时间与对照组比较均明显缩短(P<0.05)。结论:干扰素和易坦静联合治疗婴幼儿毛细支气管炎起效快,疗程短,疗效可靠,给药方便安全,值得临床推广应用。

Objective： To study the effect of interferon and Yitanjing on infants with bronchiolitis. Method： 52 infants with bronchiolitis from April 2011 to April 2012 in the hospital were randomly divided into two groups, control group was treated by oxygen, asthma and expectorant, and observation group that based on the conventional treatment was treated by interferon and Yitanjing. Clinical efficacy, symptoms, and signs disappear of the two groups were compared. Result： The cure rate of the observation group was 100%, while the control group was 65.4%, the difference was statistically significant（P〈0.05）. Cooling time, wheezing duration of remission, cough disappeared time, the lungs wheeze disappeared time, and duration of hospitalization of the observation group were shorter than those of the control group（P〈0.05）. Conclusion： Combination therapy of interferon and Yitanjing is of rapid effect, short course, and satisfactory efficacy. It is valuable in clinical application.