喜炎平水针疗法治疗慢喉痹临床分析

Clinical analysis of Xiyanping Injection hydro-acupuncture therapy in treating chronic laryngalgia

目的观察喜炎平注射液水针疗法治疗慢喉痹患者的疗效。方法将800例临床确诊的慢喉痹患者随机对照分为治疗组400例和对照组400例。治疗组应用喜炎平注射液25 mg,对照组应用喘可治注射液1 mL行双侧"喉痹"穴加天突穴位水针治疗,每3天1次,连续7次,随访3个月后比较两组疗效。结果 (1)治疗组临床疗效的总有效率为96.41%,对照组临床疗效的总效率为93.58%。两组临床疗效有显著性差异(Z=-5.702,P<0.01),治疗组疗效优于对照组。(2)治疗组内4种证型疗效比较,对热毒郁积证慢喉痹疗效最好,对照组内4种证型疗效比较,对脾肾虚弱证慢喉痹疗效最好。(3)治疗组与对照组在咽干、咽痛灼热、咽壁充血、淋巴滤泡增生的差异有统计学意义(P<0.05),治疗组疗效优于对照组,咽痒咳嗽差异有统计学意义(P<0.05),对照组疗效优于治疗组。在咽异物感、舌象、脉象方面的差异无统计学意义(P>0.05)。结论喜炎平水针疗法能有效治疗慢喉痹,无明显不良反应。

Objective To observe the effects of Xiyanping Injection hydro-acupuncture therapy in treating the patients with chronic laryngalgia. Methods 800 cases of clinically diagnosed chronic laryngalgia were randomly divided into the treat- ment group（n=400） and the control group（n=400）. The treatment group was injected with Xiyanping Injection 25rag and the con- trol group with Chuankezhi Injection 1 mL by the hydro-acupuncture in the acupoints of ＂Houbi＂ and ＂Tiantu＂, once per 3 d for continuous 7 times. Aftter 3-month following up, the curative effects were compared between the two groups. Results （ 1 ）The to- tal effective rate was 96.41% in the treatment group and 93.58% in the control group with significant difference between two groups （Z=-5.702, P〈0.01 ）.The treatment group was superior to the control group in the clinical effects. （2）In the comparison a- mong 4 syndrome patterns of the treatment group, there was the best clinical efficacy in the pyretic toxicity stasis pattern,while in the control group, the spleen kidney asthenia pattern was best. （3）In the symptoms and signs of dry pharynx, pharyngodynia, congestion of the pharyngeal wall, lymphoid follicular hyperplasia,the difference between 2 groups was statistically significant （P〈0.05）. The clinical efficacy of the treatment group was better than that of the control group. Difference in pharynx itchy and cough was statistically significant（P〈0.05 ）, showing that the clinical efficacy of the control group was better than that of the treat- ment group. There was no statistically significant difference in foreign body sensation of the pharynx, tongue presentations, pulse presentations （P〉0.05）. Conclusion Xiyanping Injection hydro-acupuncture can effectively treat chronic laryngalgia without obvious adverse reactions.