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盐酸环喷托酯与复方托比卡胺在兔外伤性白内障囊外摘除术中散瞳效果比较

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摘要 目的比较盐酸环喷托酯与复方托比卡胺在兔外伤性白内障囊外摘除术中的散瞳效果。方法实验用大白兔20只,制成双眼外伤性白内障兔子模型,并于外伤后第3天行白内障摘除术。术前记录瞳孔的大小,实验组结膜囊内滴入1%盐酸环喷托酯滴眼液,对照组滴入1%复方托比卡胺眼药水。用药后开始观察瞳孔开始散大的时间、瞳孔完全开大所需时间、瞳孔最大直径、瞳孔对光反应消失的时间及睫状肌调节恢复的时间。结果两药于点药结束后10 min之内均能达到最大瞳孔直径,两组瞳孔开始和达到最大瞳孔直径的时间及最大瞳孔直径无统计学差异;最大瞳孔直径维持时间分别为(75.00±7.75)min和(66.50±6.34)min,差异有统计学意义(P<0.05),对光反射消失时间和睫状肌调节恢复时间比较也具统计学差异。结论盐酸环喷托酯组与复方托比卡胺组相比,虽然在睫状肌调节能力的恢复时间相对较慢,但其维持最大孔径时间较长。
出处 《现代医药卫生》 2012年第14期2145-2146,共2页 Journal of Modern Medicine & Health
基金 扬州环境资源职工技术学院2010年度院级课题
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