抗氧化剂与胃粘膜保护

Antioxidants and Gastric Mucosal Protection

氧自由基在胃粘膜损 伤及溃疡病的发病机制中起着重要作用。胃粘膜本身也具有较强的抗氧化系统,包括酶类和非酶类。某些抗氧化剂通过诱导细胞保护酶活性增高,发挥对胃粘膜损伤的保护作用。抗氧化剂作为粘膜保护剂将具有很大应用前景。

Reactive oxy-en -derivedspecies are implicated in mediation of the pathogenesis of gastric mucosai damage and ulceration. Gastric mucosa has developed several endogenous antioxidant systems in-cluding enzymatic and nonenzymatic groups. Some antioxidants have protective effectsagainst gastric mucosai lesions via increasing the activities of cytoprotective enzymes. An-tioxidants will develop a new effective gastric mucosa protectant with vast prospects.