养阴逐瘀汤联合西医常规治疗喉白斑病50例

Treatment for 50 Cases of Laryngeal Leukoplakia with YangYin ZhuYuTang and Conventional Western Medicine

目的:观察养阴逐瘀汤联合西药及手术治疗喉白斑病的临床疗效。方法:将100例喉白班病患者随机分为2组,每组50例。对照组采用鼻腔表面麻醉后进行手术,术后禁烟酒,给予患者超声雾化吸入,1次/d,每次庆大霉素6万单位,地塞米松5 mg。观察组在对照组治疗的基础上给予中药养阴逐瘀汤,1剂/d,早、晚饭后服用。2组均以1个月为1个疗程,连续治疗2个疗程。结果:观察组痊愈率为84.00%,总有效率为98.00%;对照组痊愈率为70.00%,总有效率为88.00%,2组相比有统计学差异(P<0.05)。2组均未出现或发生不良反应及并发症。结论:养阴逐瘀汤联合西药及手术治疗喉白斑病临床疗效好,无不良反应。

Objective： To explore clinical effects of YangYin ZhuYuTang, western medicine and surgery in treating laryngeal leukoplakia. Method： One hundred patients were randomized into two groups on average. Operation was performed after anesthesia of nasal surface and the patients of both groups were banned from smoking and drinking, administered with ultrasonic atomizing inhalation, once each time, 60 mg/1mL of gentamycin sulfate injection and 5 mg of dexamthasone each time. Observation group received YangYin ZhuYuTartg based on the treatment given to control group, one dose per day, taking after breakfast and supper. One session was one month and both groups were treated for two consecutive sessions. Result： Cure rate and total effective rate of observation groups were 84.00% and 98.00%, superior to 70.00% and 88.00% of control group with notable differences （P〈0.05）. No adverse reaction or complication occurred in both groups. Conclusion： YangYin ZhuYuTang combined with western medicine and surgery can obtain better clinical effects in treating laryngeal leukoplakia without adverse reaction.