新生儿脐静脉置管两种封管液应用效果比较

Clinical effects of two catheter-locking solutions for umbilical venous catheterization in newborns

目的探讨新生儿脐静脉置管两种封管液应用效果。方法将72例留置脐静脉导管的新生儿配对分为两组,分别应用0.9%生理盐水(34例)、10U/mL肝素盐水(38例)在患儿输液结束后进行封管。比较两组患儿导管留置时间、导管留置相关并发症发生率。结果两组患儿导管留置天数、脐静脉导管并发症发生率比较,差异无统计学意义(均P﹥0.05)。结论 0.9%生理盐水作为脐静脉置管封管液,能有效维持管道通畅,且更加符合新生儿生理健康需求,值得临床推广应用。

Objective To investigate the clinical effects of two catheter-locking solutions for umbilical venous catheterization in newborns. Methods 72 newborns with umbilical venous catheterization were separated into two groups randomly. Catheters in the two groups were locked by 0.9% physiological saline （n=34） or 10U/ml heparin saline （n=38）, respectively. The two groups were compared in view of catheter detaining duration and catheter-related complications. Result There were no differences between the two groups in view of catheter detaining duration and catheter-related, without any difference between the two groups （P 〉 0.05 ）. Conclusion 0.9% physiological saline as the locking solution can keep the catheters unobstructed and meet the requirements of newborn＇s health.