两种口服补钾方案快速改善轻度低血钾患者血钾水平的效果

Comparison of two ways of oral therapy for hypokalemia

目的比较两种口服补钾方案对轻度低血钾患者的效果。方法回顾性分析2009年3月至2011年3月116例口服补钾患者的临床资料，其中58例患者口服氯化钾缓释片，58例患者口服改良配制的补钾液，治疗2d后，复查血钾水平。结果116例口服补钾治疗低血钾患者的低血钾情况均有所好转，其中口服补钾液患者的低血钾改善程度明显优于口服氯化钾缓释片患者[（0．492±0．242）mmol/L比（0．219±0．131）mmol／L]，差异具有统计学意义（t=2．543，P〈0．05）。结论对于轻度低血钾患者，口服补钾液效果优于口服氯化钾缓释片。

Objective To compare the effect of two ways of oral therapy for mild hypokalemia. Methods We retrospectively analyzed the clinical data of 116 cases treated by oral therapeutics for mild hypokalemia between March 2010 and March 2011. 58 cases were treated by potassium chloride sustained- release tablets, the other 58 cases by oral potassium chloride solution. We retested the serum potassium level two days after treatment. Results After treatment, serum potassium level elevated in all the 116 eases compared with baseline. The serum potassium level elevation magnitude in patients who took potassium chloride solution were larger than in patients who took potassium chloride sustained-release tablets, and there was statistically significant difference between the two methods [ （ 0. 492 ± 0. 242 ） mmol/L vs （ 0. 219 ± 0.131 ） mmol/L; t = 2. 543 ,P 〈 0.05 ]. Conclusions For mild hypokalemic patients, oral potassium chloride solution treatment is safe and more effective compared with oral potassium chloride sustained-release tablets.