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前列腺癌的转化医学 被引量:5

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摘要 前列腺癌是威胁男性健康的最常见肿瘤之一,在发达国家其发病率居男性肿瘤首位,占全部恶性肿瘤的28%;其死亡率仅次于肺癌[1]。前列腺癌的发病率和死亡率具有明显的种族差异,我国前列腺癌的发病率和死亡率虽远低于欧美国家,但近年来随着人口老龄化及生活条件的改善,其发病率呈快速上升的趋势。上海地区前列腺癌的发病率已从1990年的2.6/10万上升至2005年的16.1/10万,超过膀胱癌成为泌尿系统最常见的恶性肿瘤。从分子遗传学角度来看,前列腺癌的发生、发展是一个多因素、多阶段的过程,往往涉及多个基因的改变。近年来,
出处 《上海医学》 CAS CSCD 北大核心 2012年第5期356-358,共3页 Shanghai Medical Journal
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