参地颗粒联合阿维A治疗血热型寻常型银屑病疗效观察

The Efficacy and Serum TNF-α and IL-8 Content in the Treatment of Blood Heat Psoriasis Vulgaris by Sendi particles Combined Acitretin Capsules

目的:探讨治疗寻常型银屑病的有效方法,减少治疗中的副作用。方法:采用随机、单盲、平行对照的临床研究方法,对60个病例按时间编号,参照随机数字表将其分为两组。治疗组30例,口服参地颗粒联合阿维A;对照组30例,口服阿维A治疗,两组同时外搽凡士林,疗程12周,观察疗效、治疗前后银屑病皮疹面积和严重程度指数(PASI)积分及不良反应发生情况等,并对两组治愈患者进行3个月的随访。结果:治疗组与对照组比较,差异有显著性意义(P<0.05),治疗组优于对照组。结论:参地颗粒联合阿维A治疗血热型寻常型银屑病疗效可靠,在改善患者病情和降低复发率方面有明显优势,值得临床推广。

Objective：To investigate the effective way to reduce the side effects of treatment of psoriasis vulgaris.Methods：A randomized,single blind,parallel-group clinical study method to observe the cases are from the outpatient and inpatient laboratory for July 2011 to December 2011,a total of 60 cases,the number of time with reference to the random number table will be divided into2 groups.Treatment group,30 cases of oral ginseng particles Joint Avi A;control group（30 cases）,oral acitretin therapy in both groups Waicha Vaseline,for 12 weeks,clinical efficacy was observed before and after the treatment of psoriasis rash Area and Severity index（PASI） points and the incidence of adverse reactions,etc.,and two sets of cured patients 3 months of follow-up.Results： The treatment and control groups,the differences were significant（P〈0.05） in the treatment group than the control group.Results：Sendi granule combined with Avi A treatment of blood-heat type psoriasis vulgaris psoriasis efficacy reliable,there are obvious advantages in improving the patient’s condition,it is worth promoting.Conclusion.