颅外颈动脉硬化斑块形态与脑缺血症状关系初探

A Primary Study of Relationship between Carotid Plaque Morphology and Brain lschaemic Symptoms

目的：研究颅外颈动脉硬化性斑块形态与脑缺血症状的关系。方法：运用Ｄｕｐｌｅｘ超声对１８８例患者行颈颅外段动脉检测。将颅外颈内动脉狭窄度分成五级，颈内动脉斑块形态分成四型。结果：本研究共对３７６侧颈动脉行狭窄度检测，对２１３侧颈动脉行斑块形态学分型。结果显示。颈动脉硬化斑块的狭窄度和形态学类型与脑缺血症状的发生均有密切关系（Ｐ＜０．０１）。斑块形态学类型与狭窄度两因素之间有密切的内在联系，但斑块形态学的改变并不增加狭窄度预测脑缺血症状发生的敏感性。结论：颈动脉斑块类型随着其狭窄度的增加而改变，斑块形态不能作为预测脑缺血症状发生的独立危险因素。

Objective: To study the relationship between carotid plaque morphology and brain ischaemic symptoms. Methods: A total of 188 patients referred for carotid Duplex scanning in a 2 - year period have been included. Five carotid stenotic grades and four carotid plaque morphologic types were classified. Results: Degrees of stenosis were identified in 376 carotid bifurcations and morphologic types were classified in 213 plaques indicating that morphologic types as well as stenotic degrees were significantly associated with brain ischaemic symptoms (P < 0. 01). However, plaque typing did not add to the sensitivity of stenosis in predicting the presence of symptoms. Conclusion: Plaque type appeared to be changed with the degree of stenosis. It did not appear to represent an independent risk factor for neurologic events.