维生素E联合参苓白术丸治疗慢性乙型肝炎肝硬化疗效分析

Analysis of Therapeutic Effect on Chronic Hepatitis B Cirrhosis Treated by Vit E Combined with Shenling Baichu Pills

目的:观察维生素E联合参苓白术丸治疗慢性乙型肝炎肝硬化的临床疗效和安全性。方法:60例随机分为治疗组30例和对照组30例。两组均行保肝综合治疗,治疗组加用维生素E合参苓白术丸1,2周为一疗程。结果:治疗组ALT、AST、ALB、TBIL,Child-pugh计分,肝纤维化指标HA、LN、PCⅢI、VC改善明显优于对照组(P<0.05,P<0.01);门静脉内径和脾脏厚度改善优于对照组(P<0.05),临床疗效明显优于对照组(P<0.01)。结论:维生素E合参苓白术丸治疗慢性乙型肝炎肝硬化效果较好。

Objective ：To observe the clinical effects and the security of VitE and shenling baizhu pill on cirrhotic patients following chronic hepatitis B. Method ：60 patients were randomly divided into two groups, the control group received combined therapy, the study group received VitE and shenling baizhu pill additionally, the treatment cycle was 12 weeks. Clinical symptoms,blood hepatic function, Child -pugh score, fibrous pa- rameters were observed ; ultrasonic and pathological histology inspection were done ; Results ： After treatment, the results of ALT, AST, ALB, TBIL, Child -pugh score, HA, LN, PC m and IVC;the inner diameter of portal vein and the thinkness of spleen were all better than that of the control group. Thrombocyte raise, symptoms improvement and the divide stage of fibrous parameters decreased greatly. Conclusion ： VitE and shenling baizhu pill was effective on cirrhotic patients following chronic hepatitis B.