原发性脾肿瘤11例临床治疗分析

Treatment of 11 patients with primary splenic tumor

目的 探讨原发性脾肿瘤的临床特点及其治疗。方法 回顾性分析 1986年 8月至1997年 10月收治的 11例原发性脾肿瘤的临床资料。结果 11例中良性肿瘤 4例 ,恶性肿瘤 7例。11例均经手术切除 ,其中脾血管瘤 3例 ,脾肉芽肿 1例 ,脾血管肉瘤 4例 ,脾恶性淋巴瘤 3例。在随诊的 7例恶性肿瘤中 ,有 3例脾血管肉瘤和 1例恶性淋巴瘤分别于术后 7、9、2 8及 14个月死亡 ,1例脾血管肉瘤和 2例恶性淋巴瘤分别随诊 16、5 8及 2 2个月 ,未见肿瘤转移和复发。结论 原发性脾肿瘤应以手术治疗为主 ,良性肿瘤术后无需处理 ,对瘤体较大、分化较差的恶性肿瘤术后应进行辅助治疗。早期发现、早期治疗是提高原发性脾脏恶性肿瘤病人长期生存的唯一希望。

Objective[WT5”BZ] To discuss the clinical characteristics and treatment of primary splenic tumor.[WT5”HZ] Methods[WT5”BZ] Eleven primary splenic tumor patients were treated from Aug.1986 to Oct.1997.[WT5”HZ] Results[WT5”BZ] There were 4 benign and 7 malignant tumors. All were treated with splenectomy. Pathology: splenic hemangioma in 3, splenic granuloma in 1, splenic angiosarcomas in 4, and splenic malignant lymphoma in 3. In the 7 malignant tumor patients, 3 patients with splenic angiosarcomas and one with splenic malignant lymphoma died 7,9,28 and 14 months postoperatively. One patient with splenic angiosarcomas and two with splenic malignant lymphoma have been followed up for 16,58 and 22 months respectively without any recurrence or metastasis. [WT5”HZ]Conclusions[WT5”BZ] Splenectomy is the treatment of choice for primary splenic malignant tumor. Splenic benign tumor does not require adjuvant therapy after splenectomy. Splenic malignant tumor requires adjuvant treatment. Early detection and early treatment are crucial to increase the survival rate of primary splenic malignant tumor. [WT5”HZ]