CT引导下经皮肝穿刺无水乙醇注射联合肝动脉化疗栓塞术治疗巨块型肝癌的临床疗效研究

CT-guided Percutaneous Ethanol Injection Combined with Transcatheter Arterial Chemoembolization in Treatment of Massive Liver Cancers

目的评估CT引导下经皮肝穿刺无水乙醇注射(PEI)联合肝动脉化疗栓塞术(TACE)治疗中晚期巨块型肝癌的临床疗效。方法回顾性分析24例应用CT引导下PEI联合TACE治疗的中晚期巨块型肝癌患者的临床资料,第1次TACE+PEI治疗结束后1～3个月行CT及实验室检查。随访半年～1年。结果 24例患者治疗有效率为62.5%(15/24),半年和1年生存率分别为83.3%(20/24)和58.3%(14/24)。结论 PEI联合TACE是一种较好的治疗中晚期巨块型肝癌的方法,是TACE疗效不佳者的理想选择,具有较大临床推广应用价值。

Objective To evaluate the clinical effects of CT-guided percutanious ethanol injection（PEI） combined with transcatheter arterial chemoembolization（TACE） on moderate and advanced massive liver cancers.Methods The clinical data of 24 patients with moderate and advanced massive liver cancers receiving CT-guided PEI with TACE were analyzed retrospectively.CT and clinical laboratory underwent 1~3 month after TACE＋PEI treatment.The follow-up lasted six months~ 1 year.Results The treatment response rate was 62.5%（15/24）in 24 patients,six-month and 1-year survivals were 83.3%（20/24）,58.3%（14/24）,respectively.Conclusion PEI with TACE,a better treatment of moderate and advanced massive liver cancers and an ideal choice for those who have poor efficacy using TACE,is of great clinical application value.