无创双水平气道正压通气治疗中重症支气管哮喘临床疗效分析

Bi-level Positive airway pressure ventilation for treatment of severe bronchial asthma

目的观察无创双水平气道正压通气治疗中重症支气管哮喘的临床疗效。方法将50例患者随机分为两组。两组患者入院后均给予糖皮质激素、氨茶碱、β受体激动剂、祛痰剂、抗感染等对症治疗。治疗组同时使用无创双水平气道正压通气治疗。观察两组临床疗效、症状、体征、肺功能及血气分析的改善情况。结果治疗组临床控制率为76%,总有效率92%,对照组临床控制率为48%,总有效率64%。临床控制率、总有效率两组相比差异有统计学意义(P<0.05)。两组经治疗后日间症状评分、夜间症状评分、FEV1%、PEF%较治疗前有显著的变化(P<0.05)。结论无创双水平气道正压通气治疗中重症支气管哮喘疗效可靠。

Objective To investigate the clinical value of bi-level positive airway pressure ventilation in treatment of severe bronchial asthma.Methods 50 patients were randomly divided into 2 groups.2 groups patients were given glucocorticoid,aminophylline,β receptor agonist,expectorant agent,anti-infection and symptomatic treatment after admission.While bi-level positive airway pressure ventilation was used in the treatment group.The clinical effects,symptoms,signs,improvements in lung function were observed.Result The clinical control rate in treatment group was76%,total effective rate was 92%;the clinical control rate in control group was 48%,total effective rate was 64%.Clinical control rate,the total effective rate between 2 groups were statistically significant（P〈0.05）.In the two group,symptom scores,nighttime symptom scores,FEV1% and PEF% after treatment were significantly higher than those before treatment（P〈0.05）.Conclusion Bi-level positive airway pressure ventilation is effective in treatment of severe bronchial asthma.