摘要
目的探讨糖皮质激素治疗结节病的疗效及对预后的影响。方法回顾分析海军总医院自2000年诊断明确的155例患者的临床资料,比较糖皮质激素治疗与自然病程的预后。结果本组资料中结节病患者男女之比为1∶1.92,发病年龄集中在40～59岁之间。首发症状主要为咳嗽和胸闷,分别占61.9%,23.9%。Ⅰ期患者自愈率39.66%,Ⅱ期患者自愈率22.22%。9.68%的患者口服激素后出现严重的副反应。结论结节病临床表现无特异性,应进行密切的随访,针对不同表现的患者采用个体化治疗。
Objective To evaluate the effects of corticosteroids on the prognosis of sarcoidosis.Method Clinical data of 155 patients with sarcoidosis confirmed in General Hospital of PLA were analyzed,and the prognosis of natural course and corticosteroids therapy were compared.Results The ratio of males to females was 1 ∶ 1.92.The age of onset focused on 40-59 years.The initial symptoms mainly included congh（61.9%） and chest distress（23.9%）.The self-healing rate of stage Ⅰ and Ⅱ was 39.66% and 22.22%.There were 9.68% patients emerging serious side effects after taken corticosteroids.Conclusion No specific clinical manifestation may occur in the cases of sarcoidosis.Follow-up studies is essential.Clinical manifestations for different patients should be individualized treatment.
出处
《临床肺科杂志》
2012年第9期1577-1578,共2页
Journal of Clinical Pulmonary Medicine
关键词
结节病
糖皮质激素
自愈
sarcoidosis； corticosteroid； self-healing；
