摘要
目的分析初治结核病人强化期使用莫西沙星可减少结核病复发。方法对2005年1月至2006年12月200例初治肺结核病人随机分为两组,每组100例,初治强化期二个月Ⅰ组用药HREZ,Ⅱ组在用HREZ基础上加用莫西沙星0.4g,每天一次,巩固期六个月均为HR,观察5年病人的复发率。结果Ⅰ组病人100例5年内复发18例,复发率为18%,Ⅱ组病人100例5年内复发2例,复发率为2%。结论初治病人强化期治疗使用莫西沙星能有效地控制结核病人的复发。
Objective To analyze the effects of moxifloxacin on tuberculosis recurrence patients initially treated in intensive stage. Method 200 pulmonary tuberculosis patients initially treated from January 2005 to December 2006 were randomly divided into two groups, 100 cases in each group. In the intensive period of two months, group I received HREZ, while group II received moxifloxacin 0.4g qd based on the treatment of group I . In consolidation period of six months, two groups all received HREZ. Relapse rate of 5 years was observed in two groups. Result 18 cases recurred in group I , and relapse rate of 5 years was 18% ; 2 cases recurred in group I , and relapse rate of 5 years was 2%. Conclusion Moxifloxacin can effectively control the recurrence of tuberculosis patients initially trea- ted in intensive stage.
出处
《临床肺科杂志》
2012年第9期1634-1635,共2页
Journal of Clinical Pulmonary Medicine
关键词
结核病
莫西沙星
初治
复发
tuberculosis
moxifloxacin
initial treatment
recurrence
