一种新型手性席夫碱的合成及其在不对称环丙烷化反应中的催化性能

Synthesis of a New C_2-Symmetric Chiral Schiff Base and Its Catalytic Performance in Asymmetric Cyclopropanation

A new C 2 symmetric chiral Schiff base compound A with relatively flexible chiral environment was synthesized from L (+) tartaric acid. Its structure was determined by NMR, IR, MS etc, and its preponderant conformation was modeled by CS Chem 3D Program. The results showed that its structure is not in a plane and has a big chiral cavity. It was showed that the complex B has different catalytic performance in asymmetric cyclopropanation of styrene and DMHD (2,5 dimethyl 2,4 hexadiene) with diazoacetate. The catalytic mechanism was also discussed.