新生儿溶血病直抗结果探讨

The Discussion of the Direct Antiglobulin Experimental Results in HDN

目的:探讨直抗阴性和阳性结果与新生儿溶血病(HDN)病情的关系。方法:筛选确认HDN患儿40例,根据直抗结果分为直抗阴性组(20例)和直抗阳性组(20例),比较两组患儿首次TBIL、DBIL、NSE结果。结果:两组患儿TBIL、DBIL、NSE结果差异无统计学意义(P>0.05)。结论:直抗阴性并不能排除HDN,且直抗结果不能用于区分病情严重程度。

Objective： To investigate the difference of the direct antiglobulin negative results and the positive resuhs for HDN.Method： Screened 40 cases of HDN children, and divided into the negative group （20 cases） and the positive group （20 cases） according to direct antiglobulin experimental results. Compared the first results of TBIL , DBIL and NSE. Result ： TBIL, DBIL and NSE results between the two groups of children were no significant difference（P〉0.05）. Conclusion： The negative result of direct antiglobulin test can not use to exclude HDN, and can not be used to distinguish the severity of disease.