急性有机磷农药中毒60例临床分析

The Analysis of the Sixty Cases of the Acute Organophosphorus Pesticide Poisoning

目的：探讨急性有机磷农药中毒的临床特点及有效治疗方法，以提高对急性有机磷农药中毒的治疗水平，减少病死率。方法：回顾分析60例急性有机磷农药中毒患者的临床资料，并分析其诊治经过。结果：本组病例总治愈率为85．00％，所有轻～中度中毒的患者治愈率为100％，重度中毒患者中发病时间较短（〈4．5h）且配合血液透析或血流灌注治疗的，治愈率为88．89％，未配合接受该治疗的治愈率为75．00％，发病时间长、虽采用了各种治疗措施，其治愈率为0。结论：急性有机磷农药中毒的治愈率与患者的发病时间、中毒程度的轻重及所采取的综合治疗措施、是否及时合理地给予阿托品及胆碱酯酶复能剂等有明显关系。

Objective：To investigate the clinical characteristic and the effective treatment of the acute organophosphorus pesticide poisoning and to improve the curative effect and reduce the death rate.Method：Review and analyzed the clinical data of 60 cases of acute organophosphorus pesticide poisoning and analyzed the whole course of every case.Result：The cure rate of the cases was 85.00%, and the cure rate of all the light and moderate poisoning cases was 100%.In all the severe poisoning cases, the cure rate of the cases in which the patients received all treatments including hemodialysis or perfusion was 88.89%, and the cure rate of the cases in which the patients received every treatment except hemodialysis or hemoperfusion was 75.00%. For the patients who had received all kinds of treatments but the time in which they had gone to see a doctor was too long（〉4 - 5 hours）, however the cure rate was 0. Conclusion ：The cure rate of acute organophosphorus pesticide poisoning is related to the time in which the patients go to see a doctor, the order of severity, the treatments, whether give timely and reasonably the atropine and the cholinesterase reactivator treatments and so on.