MRI分子与功能成像诊断胰腺癌的研究新进展

Advances in magnetic resonance molecular and functional imaging to diagnose pancreatic cancer

胰腺癌早期症状不显著,早期诊断缺乏特异性,因此死亡率高.近年来,分子及功能成像发展迅速,其以分子生物学为基础,在活体状态下从分子、基因水平对胰腺癌进行更早期、更特异性的诊断.磁共振成像(magneticresonance imaging,MRI)设备具有空间分辨率高、组织对比度好等优点,因此在分子及功能成像方面应用较为广泛.本文就MR分子及功能成像在胰腺癌诊断中的应用现状及发展趋势进行综述.

Pancreatic cancer has a high mortality rate,which is generally related to the initial diagnosis coming at late stage disease combined with a lack of effective diagnostic techniques.Over the past few years,molecular-functional imaging,which can be defined as the in vivo characterization and measurement of biologic processes at the molecular and gene levels,has developed rapidly and allows diagnosing pancreatic cancer more early and specifically.Magnetic resonance（MR） imaging is widely used for molecular imaging because of the high spatial resolution.This paper reviews recent advances in MR molecular and functional imaging to diagnose pancreatic cancer.