小剂量间歇补铁法在小儿缺铁性贫血治疗中的疗效观察

Curative effect observation of low dose intermittent iron supplement in treatment of pediatric iron deficiency anemia

目的研究小剂量间歇补铁法治疗小儿缺铁性贫血(IDA)的临床疗效及副作用。方法对138例缺铁性贫血患儿进行分组,小剂量组70例,常规剂量组68例,分别进行小剂量间歇补铁治疗及常规剂量每日补铁治疗,每周复查血红蛋白(Hb),观察治疗效果。结果小剂量组与常规剂量组比较血红蛋白上升速度相同,差异无统计学意义(P>0.05),常规剂量组副作用发生率高于小剂量组,差异有统计学意义(P<0.05)。结论小剂量间歇补铁法与常规剂量补铁法治疗小儿IDA疗效相同,且副反应发生率低、程度轻,认为小剂量补铁法较好,值得临床推广。

Objective To study the clinical effects and side effects of low dose intermittent iron supplement in treating the iron deficiency anemia （IDA） in children. Methods One hundred and thirty-eight cases of children with IDA were divided into low dose group 70 eases and regular dose group 68 cases, low dose intermittent iron supplement treatment and regular close daily iron supplement treatment were administrated separately. The hemoglobin was examined weekly and therapeutic effects were observed. Results The hemoblobin increase rate was similar between low dose group and regular close group, there was no significant difference between the two groups （/9 〉 0.05）. But the side effect of regular dose group was higher than that of the low dose group, the difference had statistical significance （P 〈 0.05）. Conclusion Low dose intermittent iron supplement treatment has the same effect with regular dose iron supplement treatment, but the side effect chance is lower and the degree is lighter. The low dose intermittent iron supplement treatment is worth clinical expansion because this treatment is better.