胸腔积液中腺苷脱氨酶的临床检测意义分析

Significance of detection of adenosine deaminase in pleural effusion

目的探讨胸腔积液中腺苷脱氨酶的临床检测意义。方法选择本院结核性胸腔积液患者共35例,作为结核组;同时选择本院肿瘤性胸腔积液患者共30例,作为肿瘤组。取两组患者胸腔积液,测定腺苷脱氨酶活性。结果结核组胸腔积液中腺苷脱氨酶活性显著高于肿瘤组,差异有统计学意义(P<0.05);结核组胸腔积液中腺苷脱氨酶阳性检出率显著高于肿瘤组,差异有统计学意义(P<0.05)。结论胸腔积液患者中行胸腔积液腺苷脱氨酶活性检测有助于结核性胸腔积液和肿瘤性胸腔积液鉴别诊断,检测意义重要,值得借鉴。

Objective To explore the significance of detection of adenosine deaminase in pleural effusion. Methods Thirty five cases with tuberculous pleural effusion were selected, as tuberculosis group; at the same time, selection of neoplastic pleural 30 cases, as tumor group. Extraction of pleural effusion in two groups was done, adenosine deaminase activity was detected. Results Adenosine deaminase activity in tuberculosis group was significantly higher than that in tumor group, the difference was statistically significant （P 〈 0.05）; adenosine deaminase positive rate in tuberculosis group was significantly higher than that in tumor group, the difference was statistically significant （P 〈 0.05）. Conclusion Adenosine deaminase activity detection in patients with pleural effusion is helpful to differentiate the tuberculous pleural effusions and malignant pleural fluid, the significance of detection is important.