CT肺动脉栓塞指数的临床应用价值

The clinical value of CT pulmonary artery obstruction index

目的探讨肺动脉栓塞指数(pulmonary satery obstruction Index,PE指数)在指导临床治疗急性肺动脉栓塞(acute pulmonary embolism,APE)的临床应用价值。方法选择经CT肺动脉造影(CT pulmonary angiography,CTPA)证实的急性肺动脉栓塞患者105例,分别以PE指数30%～60%、>60%分成中、重度两组,再依据是否有溶栓禁忌症,将患者分成溶栓组和抗凝组,对每位患者治疗后的效果进行评价,分析PE指数对临床治疗急性肺动脉栓塞的指导作用。结果中度组(PE指数30%～60%)溶栓组和抗凝组治疗效果无显著差异,重度组(PE指数>60%)溶栓组比抗凝组有效率明显提高而死亡率明显降低。结论 PE指数可以作为急性肺动脉栓塞患者是否进行溶栓治疗的一项重要指标。

Objective To investigate the clinical application value of Pulmonary Artery Obstruction Index （PE Index） in guiding clinical therapy of Acute Pulmonary Embolism （APE）. Methods 105 patients with Acute Pulmonary Embolism confirmed by CTPA were chosen. Accooding to PE Index of 30% -60% or 〉60% patients were divided into moderate and severe groups. According to whether haing thrombolytic contraindications, patients were divided into thrombolytic group and anticoagulant group. Then we evaluated the effects of treatment for each patient, and analyzed the guiding function of the clinical therapy of acute pulmonary embolism by PE Index. Results The moderate group （PE Index 30%- 60%） thrombolytic group and anticoagulant group had no significant difference, the severe group （PE Index 〉 60%） thrombolytic group was significantly improved than anticoagulant group in group efficiency, and the mortality was significantly reduced. Conclusion Pulmonary embolism index can be used as an important index for guiding the clinical therapy of acute pulmonary embolism.