室温交联多孔结构分子印迹乳胶膜的制备和性能

Preparation and Properties of Ambient Crosslinking Porous Molecularly Imprinted Latex Membranes

以双丙酮丙烯酰胺(DAAM)、丙烯酸(AA)为功能性单体合成了带酮羰基的聚丙烯酸酯核壳乳液,将其与己二酸二酰肼(ADH)、模板分子、致孔剂在室温下交联成膜制备出多孔结构分子印迹乳胶膜(MILM),比较了模板分子与功能单体之间的相互作用,研究了功能单体对MILM分离性能的影响。结果表明,用乳液室温交联成膜法可制备孔隙结构发达的分子印迹膜;三种功能单体与模板分子间相互作用强弱的排序为:ADH体系>DAAM体系>AA体系;ADH、AA和DAAM对MILM交联度的影响均较大,进而影响MILM的渗透性能;与非印迹膜比较,MILM对模板分子表现出选择识别性,分离因子可达到2.0以上。

A porous molecular imprinted latex membrane （MILM） with L-Tryptophan as template molecule, adipic acid dihydrazide （ADH） as cross-linker and glucose as porogen was prepared at ambient temperature from polyacrylate core-shell emulsion incorporated with diacetone acrylamide （DAAM） and acrylic acid （AA）. The strength of interaction of functional monomers with L-Tryptophan was compared. The effects of functional monomers on the separation properties of MILM were investigated. The results show that the MILM with developed void structures can be obtained by the method proposed in this paper. The strength of interaction between the three functional monomers and L-Tryptophan is in the following order： L-Trp/ADH〉L-Trp/DAAM〉L-Trp/AA. ADH, AA and DAAM have considerable influence on crosslinking degree and consequently the permeation properties of MILM. Compared with non-imprinted membrane, the acquired MILM exhibits selective recognition behavior towards template with separation factor reaching over 2.0.