抗龋IgY原料及牙膏上清液对变形链球菌粘附作用的影响

The Effect of the Anti-dental Carious IgY and its Dentifrice on the Adherence of Streptococcus Mutans

目的:研究抗龋齿蛋黄球蛋白(IgY)原料及含该原料的牙膏上清液对变形链球菌在平衡培养液和高营养培养液中蔗糖依赖性粘附作用的影响。方法:在含0.1%蛋白胨生理盐水和含1%蔗糖的BHI培养基中加入不同浓度的抗龋IgY原料或含该原料的牙膏上清液,厌氧培养变形链球菌,采用试管贴壁实验定量计算紧密粘附的细菌百分粘附率。结果:在两种培养基中加入抗龋IgY原料或含该原料的牙膏上清液后,变形链球菌的粘附率显著下降。结论:抗龋齿蛋黄球蛋白(IgY)原料及含该原料的牙膏上清液在平衡培养液和高营养培养液中对变形链球菌的蔗糖依赖性粘附均有抑制作用。

Objective： To investigate the adherence of streptococcus mutans incubated with the anti--dental carious IgY or its dentifrice in balanced medium or high nutrient medium. Methods： S. mutans were cultured with IgY or its dentifrice of different concentrations. After anaerobic culture, the percentage of the tight adherent S. mutans was calculated. Results： After cultured with IgY and dentifrice, the rates of adhesion were lower than the control. Conclusion： The anti-dental carious IgY and its dentifrice can suppress the adherence of S. mutans cells to the glass in balanced medium and high nutrient medium.