免疫球蛋白静脉滴注治疗小儿重症肺炎的临床研究

Immunoglobulin intravenous injection in treatment of serious pneumonia children

目的探讨免疫球蛋白静脉注射治疗小儿重症肺炎的临床疗效。方法选取2010年1月-2011年12月医院收治的重症肺炎患儿52例,随机分为试验组及对照组,其中对照组采用常规治疗,而试验组加用免疫球蛋白静脉滴注。结果试验组患者的总有效率为92.31%,明显高于对照组的80.77%(P<0.05);治疗后试验组患儿的退热、肺部啰音及咳嗽消失、心力衰竭改善及住院天数分别为23、21、17、24例及(8.03±2.52)d,明显优于对照组的15、14、9、16例及(10.01±2.50)d,差异均有统计学意义(P<0.05)。结论采用人免疫球蛋白注射液治疗小儿重症肺炎,能显著地改善患儿的临床症状,提高治愈率、减轻并发症和缩短住院天数,因此值得在临床推广应用。

OBJECTIVE To explore the clinical efficacy of immunoglobulin intravenous injection in ＊reatment of serious pneumonia in the children. METHODS A total of 52 serious pneumonia children who enrolled in hospital from Jan 2010 to Dec 2011 were collected and randomly divided into the study group and the control group, the control group was performed with the routine treatment, and the study group was treated with immunoglobulin intravenous injection. RESULTS The total effective rate of the study group was 92.31%, significantly higher than 80.77% of the control group （P〈0.05）. The number of abatement of fever, rales-lost, cough-lost, congestive heart failure improvement and hospital day of the study group were 23,21,17,24, （8.03±2.52） d, and the control group were 15, 14, 9, 16 and （10. 01 ±2. 50） d, the differences were statistically significant （P〈0. 05）. CONCLUSION The immunoglobulin intravenous injection in treatment of serious pneumonia can significantly improve the clinical symptom, raise the cure rate, reduce the complications and shorten the hospital stay, which is worthy of the clinical promotion.