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曲美他嗪对老年高血压患者左室肥厚及心功能的影响 被引量:1

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摘要 目的:探讨心肌能量代谢药物曲美他嗪(TMZ)对老年高血压患者左心室肥厚及左室功能的影响。方法:64例老年高血压患者被随机分为治疗组和对照组。对照组采用常规治疗方法,治疗组在常规治疗基础上加用曲美他嗪(TMZ)口服(20mg,3次/日),疗程为6个月。记录并比较治疗前后超声检查左心室重量指数(LVMI)及左心室射血分数(LVEF)的结果。结果:对照组LVMI无明显变化,而曲美他嗪治疗组LVMI降低(P<0.05)。对照组LVEF略增加,但差异无统计学意义(P>0.05);曲美他嗪治疗组LVEF则明显改善(P<0.05)。两组间LVMI及LVEF差异比较均有统计学意义(P<0.05)。结论:在常规降压治疗基础上加用曲美他嗪,能进一步逆转左心室肥厚及改善左心室收缩功能。
出处 《求医问药(下半月刊)》 2012年第6期206-207,共2页 Seek Medical and Ask The Medicine
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