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microRNAs在脑出血后病理生理机制中的作用 被引量：2

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摘要 脑出血是一种高发病率和高死亡率的疾病,出血后的一系列继发性反应可以造成的严重的神经功能损伤。近年来,研究发现多个microRNA在脑出血后异常表达,参与了出血后的氧化损伤、炎症、水肿以及神经细胞凋亡等多个病理生理过程,从而加重了脑出血后继发性脑损伤。本文综述了目前microRNAs在脑出血后病理生理机制中作用的相关研究。
作者 王承 万曙 周永庆
机构地区 浙江大学医学院附属第一医院王忠诚神经外科中心
出处 《国际神经病学神经外科学杂志》 2012年第3期257-260,共4页 Journal of International Neurology and Neurosurgery
基金 浙江省钱江人才计划项目(2010R10069) 浙江省中医药科学研究基金(2010ZA066) 浙江省医药卫生科技计划项目(2010KYA125)
关键词 脑出血 MICRORNA 细胞凋亡 水肿 炎症
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献27

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同被引文献27

  • 1董洁,彭涛,宋鹏,尹述成,周绪红.长链非编码RNA XIST通过靶向结合miR-34a-5p调控鼻咽癌增殖[J].武汉大学学报（医学版）,2020,41(6):938-943. 被引量：2
  • 2Gagnier J J, Kellam PJ. Reporting and methodological quality of systematic reviews in the orthopaedic literature. J Bone Joint Surg Am, 2013, 95(11) : e771-e777.
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  • 5Moher D, Liberati A, Tetzlaff J, et al. Reprint-preferred re- porting items for systematic reviews and meta-analyses: the PRISMA statement. Phys Ther, 2009 , 89 ( 9 ) : 873-880.
  • 6Ma B, Guo J, Qi G, et al. Epidemiology, quality and re- porting characteristics of systematic reviews of traditional Chi- nese medicine interventions published in Chinese journals. PLoS One, 2011 , 6(5) : e20185.
  • 7Jadad AR, Moore RA, Carroll D, et al. Assessing the quali- ty of reports of randomized clinical trials: is blinding necessa- ry? Control Cliu Trials, 1996, 17(1) : 1-12.
  • 8Uthman OA, Okwundu CI, Wiysonge CS, et al. Citation classics in systematic reviews and meta-analyses: who wrote the top 100 most cited articles? PLoS One, 2013, 8 (10): e78517.
  • 9Lewin S, Oxman AD, Lavis JN, et al. SUPPORT Tools for evidence- informed health Policymaking ( STP ) 8 : Deciding how much confidence to place in a systematic review. Health Res Policy Syst, 2009 , 7 ( Suppl 1 ) : $8.
  • 10Whittington C J, Kendall T, Fonagy P, et al. Selective sero- tonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. Lancet, 2004, 363(9418) : 1341-1345.

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国际神经病学神经外科学杂志
2012年 第3期

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