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罗格列酮对2型糖尿病大鼠血清ox-LDL、ET、NO的干预作用 被引量:2

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摘要 2型糖尿病(type 2 diabetes mellitus,T2DM)的危害主要在于与之相关的动脉硬化(atherosclerosis,AS)可涉及全身多个脏器,本研究之前的实验显示糖耐量异常期及DM初期患者已存在有早期AS[1]。因此,早期发现DM人群甚至糖耐量异常人群的AS,对其进行早期干预治疗对于防治DM血管并发症以及减少与糖代谢异常相关的心、脑血管事件的发生,降低死亡率具有重要意义。本研究旨在了解OX-LDL、ET和NO与T2DM者AS发生的关系,并研究罗格列酮的干预作用。
出处 《基础医学与临床》 CSCD 北大核心 2012年第9期1093-1094,共2页 Basic and Clinical Medicine
基金 河北省自然科学基金(C2009001352)
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