喉部增生性病变患者幽门螺杆菌感染情况的初步调查

Preliminary investigation of HP infection in patients with laryngeal proliferative lesions

目的快速检测喉部增生性病变患者幽门螺杆菌(HP)感染情况,预测HP感染与喉癌发生的关系,为喉增生性病变的多方干预治疗提供依据,为患者进行快捷、客观的HP感染诊断方法。方法采用胃HP快速检测试纸,检测喉增生性病变组织及其患者牙垢HP的感染情况。结果 175例喉增生性病变患者的牙垢及其190份组织样本中,HP感染阳性率分别为100%和71%。结论 HP感染与喉癌及癌前期病变的发病可能有密切的相关性。

OBJECTIVE To quickly detect the HP infection in patients with laryngeal proliferative lesions and to predict the relationship between the HP infection and the pathogenesis of laryngeal cancer.METHODS The HP infection in the tissues of laryngeal proliferative lesion and in the tartar of patients with laryngeal proliferative lesion was detected with the gastric rapid paper test.RESULTS The positive expression rates of HP infection in the tartar of 175 patients with laryngeal proliferative lesions and in 190 tissue specimens of the laryngeal proliferative lesions in 175 patients were 100% and 71% respectively.CONCLUSION HP infection may be correlated positively with the pathogenesis of the laryngeal precancerous lesions and laryngeal cancer.