荧光假单胞菌抗生性代谢产物合成相关基因的研究现状

The Antibiotic Metabolites Genes of Pseudomonas fluorescens

荧光假单胞菌(Pseudomonas fluorescens)是一种重要的植物根际促生菌,它能够产生藤黄绿脓菌素、2,4-二乙酰基藤黄酚、硝吡咯菌素、吩嗪-1-羧酸等抗生性次级代谢产物,可抑制多种病原物,在农作物土传病害的生物防治研究中具有重要意义。总结了荧光假单胞菌中已确立的抗生性次级代谢产物的合成机制,重点阐述了相关基因的结构、功能,以及利用生物工程技术对荧光假单胞菌进行遗传操作的最新进展,同时对荧光假单胞菌在生物防治中的应用和其作为生防菌剂的前景进行了展望。

Pseudomonas fluorescens is an important kind of plant growth-promoting rhizobaeteria （PGPR）. It can produce many secondary metabolites, such as pyoluteorin, 2, 4-diacetylphloroglucinol, pyrrolnitrin and phenazine-l-carboxyl acid. These antibiotics play a major role in suppression of many pathogens. The synthesis mechanisms of the secondary metabolites in Pseudomonas fluorescens, especially the structures and functions of the related genes were summarized. At the same time, the applications of Pseudomonas fluorescens in biological control are presented.