急性下肢深静脉血栓形成治疗后血栓后综合征发生率的临床研究

Clinical Study on Postthrombosis Syndrome Incidence Rate after Treatment of Acute Lower Extremity Deep Vein Thrombosis

目的比较急性下肢深静脉血栓形成（LEDVT）不同方法治疗后血栓后综合征的发生率。方法回顾性分析152例急性LEDVT患者的临床资料，根据不同溶栓方法将患者分为三组：A组：经足背静脉溶栓组；B组：单纯cDT组；C组：球囊扩张辅助的CDT组。Villalta评分诊断血栓后综合征（PTS）的发生。结果出院后12个月及末次随访时C组PTS发生率分别为（4．5％，11．4％），均明显低于A（32．8％，58．6％）、B两组（18％，38％），均有显著统计学差异（χ2=31．3，P=0．000）。结论球囊扩张辅助CDT能有效降低PTS的发生率，值得临床应用及推广。

Objective To study the post-thrombotic syndrome incidence rate after treatment post-thrombotic syndrome incidence rate after treatment with different methods.Methods A retrospective analysis of clinical data of 152 patients with acute low extremity deep vein thrombosis（DVT） were admitted to our department from November 2006 to March 2011.According to different thrombolytic methods the patients were divided into three groups：Group A：thrombolysis though the dorsal venous;Group B：CDT;Group C：balloon assisted CDT. Villalta scale was used to diagnosis of post-thrombotic syndrome occurs.Results After discharge 12 months and at the last follow-up Group C PTS incidence rates（4.5%,11.4%）,were significantly lower than those of Group A（32.8%,58.6%）,Group B（18%,38%）,with significant difference（χ2=31.3,P=0.000）.Conclusion Balloon assisted CDT can effectively decrease the incidence of PTS,being worthy of clinical application and promotion.