氯胺酮复合不同比例异丙酚静脉麻醉在妇科小手术中的应用

The application on the combined intravenous anesthesia with ketamine and propofol in different proportion for small gynecologic operation

目的探讨氯胺酮复合不同比例异丙酚静脉麻醉在妇科小手术中的效果。方法选取90例妇科小手术患者采用抽签法分为Ⅰ组、Ⅱ组、Ⅲ组,分别采用氯胺酮0.50 mg/kg复合异丙酚0.25、0.50、1.00 mg/kg进行静脉复合麻醉,记录患者的年龄、术中生命体征、体质量、麻醉恢复时间、手术时间、术中体动反应及术中、术后其他不良反应。结果①3组患者术中的体动反应比较差异有统计学意义(P<0.05)。②Ⅰ组、Ⅲ组患者术后血压均较术前降低,差异有统计学意义(P<0.05)。③3组患者均未发生循环系统、呼吸系统的严重并发症。结论 0.50 mg/kg氯胺酮复合0.50 mg/kg异丙酚对妇科小手术血流动力学的影响最小。

Objective To compare the anesthetic effects on the combined intravenous anesthesia with ketamine and propofol in different proportion for small gynecologic operation. Methods Ninety patients who needed small gynecologic operation were selected and randomly divided into 3 groups, group Ⅰ ： combined intravenous anesthesia with ketamine 0.50 mg/kg and propoful 0.25 mg/kg; group Ⅱ： combined intravenous anesthesia with ketamine 0.50 mg/kg and propofol 0.50 mg/kg; gn）up Ⅲ ： combined intravenous anesthesia with ketamine 0.50 mg/kg and propofol 1.00 mg/kg. Observations were made over body weight and age, vital signs, operation time, recovery time, responsive body movements and side cfiects. Results （1） The frequency of body movement was lower in group Ⅱ （10%） than in group Ⅰ （40%） and Ⅲ （20%）. （2 The blood pressure of group Ⅰ was significantly decreased after anesthesia than before anesthesia. （3） There were no respiratoy and circulatory complications in m groups. Conclusion Combined intravenous anesthesia with ketamine 0.50 mg/kg and propofol 0.50 mg/kg can offer the most stable hemodynamics for small gynecologic operation.