摘要
目的探讨曲美他嗪治疗冠心病合并慢性心力衰竭的临床疗效和安全性。方法将248例慢性心力衰竭患者按照随机数字表法随机分为观察组和对照组各124例。对照组采用常规治疗,观察组在常规治疗的基础上联合曲美他嗪治疗,治疗6个月后比较两组治疗效果。结果观察组总有效率89.52%,明显高于对照组,组间比较差异有统计学意义(P<0.05);观察组不良反应发生率为6.45%,明显低于对照组,组间差异有统计学意义(P<0.05)。结论在常规治疗的基础上联合应用曲美他嗪治疗慢性心力衰竭,可有效提高疗效,值得临床推广应用。
Objective To study clinical efficacy and safety of trimetazidine on coronary heart disease combined with chronic heart failure.Methods 248 patients with chronic heart failure patients according to random number table method were randomly divided into trial group and control group,each 124 cases.Control group was used by routine treatment,the observation group based on routine treatment combined application of trimetazidine.The treatment effect was observed.Results The total effective rate of observation group was 89.52%,significantly higher than those in the control group（P〈0.05）.The adverse reaction of observation group was 6.45%,and adverse reaction rate was significantly lower than that of the control group（P〈0.05）.Conclusion Based on routine treatment combined application of trimetazidine on chronic heart failure can effectively enhance the curative effect.
出处
《西部医学》
2012年第8期1551-1552,共2页
Medical Journal of West China
关键词
慢性心力衰竭
曲美他嗪
疗效
不良反应
Chronic heart failure
Trimetazidine
Curative effect
Adverse reaction
