急性前壁ST段抬高型心肌梗死直接PCI联合应用血栓抽吸导管的临床研究

Acute Anterior ST-Segment Elevation Myocardial Infarction PCI Thrombus Aspiration Catheter in Combination Clinical Studies

目的探讨直接PCI联合应用血管抽吸导管治疗急性前壁ST段抬高型心肌梗死的临床疗效。方法前瞻性研究80例急性前壁ST段抬高型心肌梗死患者,随机分成直接PCI治疗组和直接PCI联合应用血管抽吸导管治疗组各40例,分别记录入选患者的一般情况、病史特征、化验检查、心电图、手术并发症、术后恢复情况等。比较两组患者的临床特征,治疗后的心肌酶学峰值变化及心电图ST段回落的差异。结果两治疗组治疗前的临床特征无明显差异(P>0.05)。与直接PCI组相比心电图ST段回落>50%比率明显升高(P<0.05)。直接PCI联合应用血管抽吸导管治疗组心肌酶CK-MB峰值明显低于直接PCI组(P=0.038)。结论直接PCI联合应用血栓抽吸导管治疗急性前壁ST段抬高型心肌梗死能够更大程度的达到心肌再灌注,减小心肌梗死面积的效果。

Objective Combination of direct PCI for acute anterior vascular aspiration catheter ST-segment elevation myocardial infarction in clinical efficacy. Method Prospective study of 80 cases of acute anterior ST-segment elevation myocardial infarction were randomly divided into direct and immediate PCI, PCI combined group of vascular aspiration catheter treatment group, 40 cases were selected for the patient＇ s general record, medical history characteristics, laboratory examination, ECG, surgical complications, postoperative recovery and so on.Two groups were compared clinical features, treatment of serum creatine kinase peak ECG ST segment changes and differences.Rasult The two pre-treatment, no significant difference in clinical characteristics （P 〉 0.05 ） .PCI group compared with the ECG ST segment 〉 50%ratio was significantly higher （P 〈 0.05 ） . Primary PCI combined vascular aspiration catheter treatment group enzymes CK-MB peak was significantly lower than the PCI group （P =0.038 ） .Conc I us i on The combination of direct PCI thrombus aspiration catheter treatment of acute anterior ST-segment elevation myocardial infarction can achieve a greater degree of myocardial reperfusion, reduced infarct size.