乌司他丁对Oddi括约肌功能影响的临床研究

目的观察乌司他丁对Oddi括约肌功能的影响。方法选择研究对象30例,随机分为乌司他丁2500U/min组和5000U/min组,各15例,观察用药前、用药10min和20min后SOBP、SOCA、SOF和CBDP的变化。结果乌司他丁2500U/min组:SOBP、SOCA和SOF在用药后20min均下降(P<0.05)。乌司他丁5000U/min组:SOBP、SOF在用药后20min和10min均下降(P<0.05);SOCA在用药后20min下降(P<0.05)。结论乌司他丁可以降低SOBP、SOCA、SOF。

Objective To observe the effect of Ulinastatin on sphincter of Oddi function influence Methods The selection of study subjects in 30 cases, Randomly divided into Ulinastatin in 2500U/min group and 5000U/min group, 15 cases each. Observed the SOBP,SOCA.SOF and CBDP changes after taking 10 min and 20 min. Results ulinastatin 2500U/min： SOBP, SOCA and SOF in 20 min were decreased （P 〈0. 05）. Ulinastatin on 5000U/min： SOBP, SOF in 20 min and 10 min were decreased （P 〈 0. 05） ; SOCA in 20 min was decreased（P 〈 0. 05 ）. Conclusion Utinastatin can reduce SOBP, SOCA, and SOF.