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急性非ST段抬高性心肌梗死患者早期N-末端脑钠肽前体水平对其预后的影响 被引量：1

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摘要 目的探讨急性非ST段抬高性心肌梗死(NSTEMI)患者住院早期血浆N-末端脑钠肽前体(NT-proBNP)对其预后的影响。方法采用酶联免疫吸附法(ELISA)测定127例AMI患者住院早期血浆NT-proBNP水平,并与左室射血分数(LVEF)、1年主要不良心脏事件(MACE)对比分析。结果 NSTEMI早期患者血浆NT-proBNP水平为(375.3±98.4)pg/ml,与LVEF呈负相关(r=-0.447,P<0.01)。1年期发生MACE患者的血浆NT-proBNP水平明显高于未发生MACE者(463.4±58.3pg/mlvs246.6±103.9pg/ml,P<0.01)。结论 AMI患者血浆NT-proBNP水平与LVEF呈负相关。检测血浆NT-proBNP水平可预测AMI患者梗死面积、心功能及心血管事件的发生情况。
作者 杨帆 宁新惠 向小平
机构地区 北京市第六医院CCU病区
出处 《中国实用医药》 2012年第20期81-81,共1页 China Practical Medicine
关键词 急性非ST段抬高性心肌梗死 N-末端脑钠肽前体 预后
分类号 R542.22 [医药卫生—心血管疾病]
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中国实用医药
2012年 第20期

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