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肿瘤引流淋巴结在肿瘤免疫中的作用

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摘要 肿瘤引流淋巴结(tumor-draining lymph node,TDLN)是肿瘤细胞沿淋巴管所能到达的淋巴结,是肿瘤免疫发生的部位,也是肿瘤诱导树突状细胞(dendritic cells,DC)首先迁移到的地方.在TDLN中随着免疫系统对肿瘤抗原的识别和致敏,产生的肿瘤特异性CD4+T细胞和CD8+T细胞,进入肿瘤灶协同杀灭肿瘤细胞.因此,TDLN是机体抗肿瘤免疫反应的开始和维持部位,也是机体免疫系统对肿瘤产生耐受的关键部位.
出处 《河北医科大学学报》 CAS 2012年第8期974-977,共4页 Journal of Hebei Medical University
基金 河北省自然科学基金资助项目(C2011206145)
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  • 1Dominik Rüttinger,Rui Li,Walter J. Urba,Bernard A. Fox,Hong-Ming Hu.Regression of bone metastases following adoptive transfer of anti-CD3-activated and IL-2-expanded tumor vaccine draining lymph node cells[J].Clinical and Experimental Metastasis.2004(4)
  • 2Shinichi Sameshima,Keisuke Sakai,Hirokazu Nagawa,Nelson Tsuno,Joji Kitayama,Tetsuichiro Muto.Correlation of the therapeutic effect of activated tumor-draining lymph node cells with specific interferon-γ production in vitro[J].Surgery Today.1999(1)
  • 3Mitsuhiro Takenoyama,Kosei Yasumoto,Mamoru Harada,Keizo Sugimachi,Kikuo Nomoto.Antitumor response of regional lymph node lymphocytes in human lung cancer[J].Cancer Immunology Immunotherapy.1998(4)
  • 4Saykin AJ,,Ahles TA,McDonald BC.Mechanisms of chemotherapy-induced cognitive disorders: neuropsychological, pathophysiological, and neuroimaging perspectives[].Seminars in Clinical Neuropsychiatry.2003
  • 5Stevenson FK.Tumor vaccines[].The FASEB Journal.1991
  • 6Sameshima S,Sakai K,Nagawa H,Tsuno N,Kitayama J,Muto T.Correlation of the therapeutic effect of activated tumor- draining lymph node cells with specific interferon-γ production[].Surgery Today.1999
  • 7Tuttle TM,Inge TH,McCrady CM,Bethke KP,Bear HD.Activation of CD8+ murine T cells from tumor-draining lymph nodes by phorbol dibutyrate plus calcium ionophore[].Journal of Immunotherapy.1992
  • 8Xiu FM.The research evolution on the immunologic property and antitumor mechanism of tumor-draining lymph node cells[].Guo Wai Yi Xue Mian Yi Xue Fen Ce.1995
  • 9Imoto H,Osaki T,Taga S,Ohgami A,Ichiyoshi Y,Yasumoto K.Vascular endothelial growth factor expression in non-small-cell lung cancer: prognostic significl carcinoma[].Journal of Thoracic and Cardiovascular Surgery.1998
  • 10Tanigawa K,Craig RA,Stoolman LM,Chang AE.Effects of tumor necrosis factor-α on the maturation of tumor-reactive effector T cells[].Journal of Immunotherapy.2000

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