容桂地区育龄妇女多囊卵巢综合征患病率及临床特征调查

Investigation on prevalence and clinical characteristics of women at childbearing age with polycystic ovary syndrome in Ronggui area

目的:调查容桂地区育龄妇女多囊卵巢综合征(PCOS)的患病率,探讨该地区PCOS的临床特点。方法:采取整群随机抽样的方法抽取1 000例育龄妇女作为调查对象。按照ESHRE/ASRM诊断标准,进行问卷调查、体格检查及超声检查。对于可疑PCOS者,于第二天空腹抽血检测性激素6项、空腹血清胰岛素、空腹血糖。患者确诊后,抽取相同例数正常对照人群同时进行相同指标检测,比较正常对照组和PCOS组的生化指标。结果:在接受调查的1 000例本地区育龄妇女中确诊PCOS病例63例,占全部调查人群的6.3%。PCOS患者的临床表现包括不孕、卵巢多囊性改变、月经异常、痤疮、多毛、肥胖等,伴有性激素及血清胰岛素水平的改变。结论:本地区育龄妇女PCOS患病率为6.3%,临床表现以卵巢多囊性改变、月经异常、肥胖为主。

Objective：To investigate the prevalence of polycystic ovary syndrome（PCOS） in women at childbearing age in Ronggui area,explore the clinical characteristics of PCOS in the area.Methods：Cluster random sampling method was used to select 1 000 women at childbearing age as respondents;questionnaire survey,physical examination,and ultrasonography were performed according to ESHRE/ASRM diagnostic criteria.For the women suspected of PCOS,six items of sex hormones,fasting serum insulin,and fasting blood glucose were detected on the second day by Abstracting fasting blood samples.A total of 1 000 normal women were selected as control group after definite diagnosis,and the same indexes were detected,the biological indexes were compared between control group and PCOS group.Results：Among 1 000 women of childbearing age in the area,63 women were diagnosed as PCOS definitely,accounting for 6.3% of all the respondents.The clinical manifestations of patients with PCOS included infertility,polycystic ovary,menstrual disorder,acne,hypertrichosis,and obesity,accompanied with changes of sex hormones and serum insulin levels.Conclusion：The prevalence of PCOS in the women of childbearing age in Ronggui area was 6.3%,the main clinical manifestations included polycystic ovary,menstrual disorder,and obesity.