3-氧代-α-环柠檬醛缩二甲醇的合成研究

Study on the Synthesis of 3-Oxo-α-cylocitral-dimethylacetal

以α-环柠檬醛为原料,先经缩醛反应,再采用NHPI与乙酰丙酮亚钴为催化剂活化分子氧氧化制备得到3-氧代-α-环柠檬醛缩二甲醇,两步收率67.2%。

α - Cyclociral could be converted to its corresponding methylal via methylalization. Then 3 - oxo-α -cylocitral- dimethylacetal could be synthesized from the methylal via oxidation with molecular oxygen catalyzed by NHP! and Co（AcAc） 2. The overall yield was 67.2%.