基于中医传承辅助系统的治疗中风经方组方规律分析

Analysis on Composition Principles of Classical Prescriptions for Stroke by Using Traditional Chinese Medicine Inheritance System

目的:基于中医传承辅助系统(TCMIS)软件(V1.1),分析治疗中风经方的组方规律。方法:搜集历年文献中所报道的治疗中风的经方,录入中医传承辅助系统(V1.1),采用软件集成的改进互信息法、复杂系统熵聚类、无监督的熵层次聚类等无监督数据挖掘方法,分析治疗中风经方的组方规律。结果:基于对筛选出的92个治疗中风经方的分析,确定处方中药物出现的频次,演化得到核心组合26个、新处方4个。结论:明确了经方治疗中风的组方规律,表明中医传承辅助系统可实现对方剂数据录入、管理、查询和分析,是一个有价值的中医药研究辅助工具。

Objective： Using Traditional Chinese Medicine Inheritance System （TCMIS） to analyze the composing principles of the classical prescriptions for stroke. Method： Collect the classical prescriptions for stroke reported in the literature over the years, then enter into the TCMIS, by using revised mutual information, complex system entropy cluster and unsupervised hierarchical clustering to analyze composing principles. Result： Based on the analysis of 92 cases of the classical prescriptions, the frequency of each herb included in the database is computed, twenty-six core combinations and 4 new prescriptions are mined from the database. Conclusion. TCMIS can be used to enter, administrate, search and analyze the prescriptions and is a helpful tool for the research of traditional Chinese medicine.