天麻注射液治疗丛集性头痛40例

Gastrodin Injection in the Treatment of Cluster Headache Clinical Observation of 40 Cases

目的:观察天麻注射液治疗丛集性头痛(cluster headache,CH)的临床疗效。方法:将80例符合入选标准的CH患者随机分为观察组、对照组各40例。两组患者均给予尼莫地平,40 mg/次,3次/d,口服。观察组在此治疗基础上加用天麻注射液800 mg+5%葡萄糖注射液500 mL静脉点滴,1次/d。两组均以1周为1个疗程,治疗2个疗程后观察两组患者临床疗效及治疗前后疼痛症状积分的变化及不良反应的发生情况。结果:治愈率观察组为77.50%,对照组为62.50%,两组差异显著(P<0.05);总有效率观察组为92.50%,对照组为82.50%,两组差异显著(P<0.05)。两组治疗后疼痛症状积分分别为(2.12±0.71),(4.13±0.31)分,与治疗前相比差异明显(P<0.05),观察组改善较对照组明显(P<0.05)。两组患者均顺利完成治疗,均未出现明显的不良反应。结论:天麻注射液治疗CH临床疗效显著。

Objective： To observe the clinical efficacy of gastrodin injection in the treatment of cluster headache （CI-I）. Method： Eighty cases reached the selection standard for CH patients were randomly divided into two groups, the control group and the observation group with 40 cases in each. Two groups were given nimodipine, 40 mg, tid, orally. The observation group was given gastrodin injection in addition, 800 mg in 5% glucose （500 mL） , iv drip, daily. The two groups were treated for 1 weeks as a course. The clinical efficacy of the two groups before and after 2 courses was evaluated for pain symptom and adverse reactions. Result： The cure rate of the treatment group was 77.50% , and 62.50% in the control group. Two groups showed significant difference （P 〈 0.05）. The total efficiency in treatment group was 92.50%, and 82.50% in control group, with significant difference （P 〈0.05）. In two groups, after the treatment pain symptom scores were （2.12±0.71 ） and （4. 13 ±0. 31 ） accordingly, compared with those before treatment they were significant （P 〈 0.05）. The observation group showed more improvement than in the control with significance （P 〈 0.05）. Two groups of patients were smoothly pasted the treatments without any obvious adverse reactions. Conclusion： Gastrodin injection is effective in the treatment of CH.